4 = Patient shows clear-cut evidence of memory deficit during interview with clinician, including decreased memory of current and recent events, decreased ability to travel or handle finances, inability to perform complex tasks. Patient may also deny there is any problem with his/her memory even though it is evident to friends and family.
5 = Patient can no longer handle activities of daily life without some assistance; patient is unable to recall a major aspect of current life such as own address or telephone number, and may have trouble choosing proper clothing to wear (e.g. deciding whether a coat is required).
6 = Patient is largely unaware of all recent events and experiences; may forget spouse's name, may become incontinent, may show personality changes.
7 = Patient loses all verbal abilities over the course of this stage; patient is incontinent and requires help with feeding and toileting; patient begins to lose basic motor skills (e.g. ability to walk).
Further Reading:
The GDS scale was originally presented by B. Reisberg, S. Ferris, M. de Leon and T. Crook ("The global deterioration scale for assessment of primary degenerative dementia," in American Journal of Psychiatry, vol. 139, pp/. 1136-1139.)
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